Publication details

Authors: Sangeetha, K.; Roy, A.; Singh, S.; Lee, B.; Kumta, P. N. 
Title: Novel alginate based coatings on Mg alloys 
Type: Journal Article 
Publisher: Materials Science and Engineering B-Advanced Functional Solid-State Materials 
Year: 2011 
Volume: 176 
Issue: 20 
Start Page: 1703 
End Page: 1710 
DOI: 10.1016/j.mseb.2011.08.004 
Abstract: Coatings on yttrium doped magnesium (Mg4Y) alloy substrates were prepared using alginate hydrogels by dip coating method to improve the surface bioactive properties of the substrate. Furthermore, composite coatings containing nano-sized calcium phosphate corresponding to hydroxyapatite (HA) phase entrapped within alginate hydrogel were also synthesized on the Mg4Y substrates. Surface characteristics of these coated substrates have been investigated using FTIR-ATR, SEM and EDS. The results show that the coatings with alginate alone are not stable in vitro; however, incorporation of NanoCaPs slightly improves the stability of these coatings. In addition, these composite coatings showed cell attachments with fibronectin incorporation. These results indicate that alginate hydrogels have the potential to be used as bioactive coating materials for different biofunctional applications. (C) 2011 Elsevier B.V. All rights reserved. 
Keywords: hydrogel, alginate, cross-linking, magnesium substrates, coating, in-vivo corrosion, calcium alginate, magnesium alloys, sodium alginate, cell-adhesion, fibronectin, hydrogels, proteins, implants, delivery