Zhongyun Dong
Associate Professor
Department of Internal Medicine, Hematology-Oncology Division
College of Medicine, University of Cincinnati
Cincinnati, OH 45243
Tel (513) 558-2176
Fax (513) 558-6703
E-mail: dongzu@ucmail.uc.edu
A. Education
Anhui Medical College, Anhui, P.R. China Medicine MD/1983
Peking Union Medical College, Beijing, China Immunology MS/1986
Peking Union Medical College, Beijing, China Immunology PhD/1989
University of Texas MD Anderson Cancer CTR Cancer Biology Post-doc 1989-1991
B. Appointment
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2004-present
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Associate Professor, Dept. of Internal Medicine, Hematology-Oncology Division, University of Cincinnati College of Medicine, Cincinnati, OH
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2004
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Associate Professor, Dept. of Cancer Biology, University of Texas M.D. Anderson Cancer Center (UTMDACC) Houston, TX 77030
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1997-2004
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Assistant Professor, Dept. of Cancer Biology, UTMDACC
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1993-1997
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Assistant Professor (non-tenure track), Dept. of Cancer Biology, UTMDACC
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1991-1993
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Research Associate, Dept. of Cancer Biology, UTMDACC
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1986-1989
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Assistant Professor, Dept. of Immunology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing, P. R. of China
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C. Publications
Most relevant publications
- Zhang, F., Lee, J., Lu, S., Pettaway, C. A., and Dong, Z. Blockade of transforming growth factor-b signaling suppresses progression of androgen-independent human prostate cancer in nude mice. Clin. Cancer Res. 11:4512-4520, 2005.
- Zhang, F., Lee, J., Wang, D., Dong, Z. Differential growth of interferon-b-engineered tumor cells in nude and interferon receptor-null mice. J. Cytokine & Interferon Res., 26:108-118, 2006
- Shi, D., Lian, J., Wang, W., Liu, G., He, P., Dong, Z., Wnag, L., Ewing, R.C., Lucinescent carbon nanotubes by surface functionalization. Adv. Materials. 18:189-193, 2006.
- Lu, W., Su, J., Kim, LS, Bucana, CD., Donawho, C., He, J., Fidler, IJ., Dong, Z. Active specific immunotherapy against occult brain metastasis. Cancer Res. 63:1345-1350, 2003.
- Dong, Z., Liu, Y., Lu, S., Wang, A., Lee, K., Wang, L. H., Revelo, M., and Lu, S. Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer. Mol Endocrinol, 20: 2315-2325, 2006.
Most significant publications
- Dong, Z., Yoneda, J., Kumar, R., Fidler, I.J. Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce GM-CSF. J. Exp. Med., 188:755-763, 1998.
- Dong, Z., Kumar, R., Xiulan, Y., and Fidler, I.J. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis Lung carcinoma. Cell, 88:801-810, 1997.
- Dong, Z., Radinsky, R., Fan, D., Tsan, R., Bucana, C. D., Wilmanns, C., and Fidler, I. J. Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J. Natl. Cancer Inst., 86: 913-920, 1994.
- Dong, Z., Qi, X., and Fidler, I.J. Tyrosine phosphorylation of MAP kinase is necessary for activation of murine macrophages by natural and synthetic bacterial products. J. Exp. Med., 173: 1071-1077, 1993.
- Dong, Z., Radinsky, R., Fan, D., Tsan, R., Bucana, CD., Wilmanns, C., and Fidler, I.J. Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J. Natl. Cancer Inst., 86: 913-920, 1994.
D. Synergistic Activities
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1999-2002
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Member, California Cancer Research Program, Biomedical A Study Section
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1999 ad hoc
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Member, California Breast Cancer Research Program, Biomedical Study Section
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2000
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Member, Prostate Cancer Research Program Study Section, Group 1, Department of Defense, CDMRP-2000
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1996-present
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Reviewer for many scientific journals, including Nature Medicine, Immunology, Cancer Research, Clinical Cancer Research, Journal Leukocyte Biology, Cancer Letter, Journal of Interferon and Cytokine Research
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E. Collaborators & Other Affiliations
1. Collaborators and Co-Editors:
Drs. Isaiah J. Fidler, Catherine A. O’Brian, Curtis A. Pettaway, Colin Dinney, and Cora D. Bucana: All these collaborators are from University of Texas (UT) M.D. Anderson Cancer Center, Houston, TX.
2. Graduate and Postdoctoral Advisors:
Graduate Advisor: Dr. Youhui Zhang, Beijing, P. R. China
Postdoctoral advisor: Dr. Catherine A. O’Brian, UT M.D. Anderson Cancer Center
3. Thesis Advisor and Postgraduate-Scholar Sponsor:
Thesis Advisor: Dr. Youhui Zhang, Beijing, P.R. China
Postgraduate-Scholar Sponsor: Isaiah J. Fidler, UT M.D. Anderson Cancer Center.
